PARACETAMOL
The 30-Minute Medicine Problem
How India's largest ePharmacy is building an in-house quick-commerce engine across cities and why moving medicines in under an hour is far more complicated than it looks
Tylenol use in pregnancy may be linked with uterus, ovary changes in daughters
A recent study suggests Tylenol use by mothers during pregnancy may affect infant reproductive organ development. Researchers observed smaller ovaries and uteruses in three-month-old girls exposed to the drug. This exposure was also linked to fewer ovarian follicles and lower reproductive hormone levels. Long-term follow-up is needed to determine implications for future fertility and menopause timing. Current guidelines still recommend Tylenol as safe for pregnancy pain and fever relief.
India pharma production hit by propane shortage; vitamin, hormone supply at risk
India’s pharmaceutical industry is facing the risk of medicine shortages as a propane gas crunch forces several manufacturing units to partially or fully shut operations, disrupting production of key drugs including paracetamol, vitamins and hormones.
Not just tablets, paracetamol is hidden in 5 everyday products — experts warn of overdose risk
Experts are raising concerns about the widespread use of paracetamol, a common painkiller found in numerous over-the-counter medications. Accidental overdoses are frequent, leading to potential liver damage and even fatalities. Health officials urge caution, emphasizing the importance of reading labels and consulting pharmacists to avoid exceeding the recommended daily dosage, especially during cold and flu season.
Paracetamol to PAN-D: CDSCO finds over 50 sub-standard drugs. Check full list of medicines
The Central Drugs Standard Control Organisation (CDSCO) has flagged over 50 drugs, including Paracetamol, as 'not of standard quality'. The report highlights concerns with various medications such as calcium and vitamin D3 supplements, anti-diabetes pills, and high blood pressure medicines. Some pharmaceutical companies have denied responsibility, claiming the drugs are spurious.
Fairfax, Bain look to buy Gujarat API company Farmson
Canadian billionaire Prem Watsa's Fairfax Group and Bain Capital are in competition for a buyout of Farmson Basic Drugs, a leading API maker in India valued at ₹4,000 crore. Founded in 1969, Farmson is a major paracetamol manufacturer with a revenue of ₹1,750 crore in FY24. The company's concentrated focus on paracetamol production is a strength, but limited R&D poses challenges for diversification.
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Govt bans 14 fixed dose combination drugs, cites they may involve risk to people
The expert committee said that there is "no therapeutic justification for this FDC (fixed dose combination) and the FDC may involve risk to human beings. Hence, in the larger public interest, it is necessary to prohibit the manufacture, sale or distribution of this FDC under section 26 A of the Drugs and Cosmetics Act, 1940. In view of the above, any kind of regulation or restriction to allow for any use in patients is not justifiable."
NPPA revises ceiling prices of 128 formulations
The National Pharmaceutical Pricing Authority (NPPA) has also fixed the retail price of 12 scheduled formulations under Drugs (Prices Control) Order, 2013 (NLEM 2022). The retail price of one tablet of anti-diabetes combination drug Glimepiride, Voglibose & Metformin (extended release) has been fixed at Rs 13.83. Similarly, retail price of one tablet of Paracetamol, Phenylephrine Hydrochloride, Diphenhydramine Hydrochloride and Caffeine has been fixed at Rs 2.76.
Costs of 127 medicines set to go down post NPPA's 5th price cap
Among the 127 medications on the NPPA's list are paracetamol, amoxycillin, rabeprazole, and metformin. Patients frequently make use of many of these. The price of paracetamol (650 mg), which is sold for Rs 2.3 per tablet, has been restricted at Rs 1.8.
Scientists issue warning over new side effects of taking Paracetamol
Over-the-counter drug, paracetamol, has been found to produce a strange effect on people. Those who consume this drug more often are less fearful of risky activities, according to scientists in the US.
Granules India Q2 Results: Profit jumps 80% boosted by Paracetamol sales
The company said 51% of its revenue came from finished dosages, which is its biggest business. Active pharmaceuticals ingredients and pharmaceutical formulation intermediates contributed 29% and 20%, respectively, to its revenue.
19 fixed-dose combinations drugs under radar
These cocktail drugs were licensed for manufacture and marketed by the state licensing authority. The 19 FDCs are commonly used for conditions like headache, migraine, arthritis, muscular pain, nausea, vomiting, among others. "There are 19 FDCs which require further generation of data," said the notice from drug regulator VG Somani in a note dated August 27.
Demand for Covid drugs down, says Cipla Global CFO
The third wave has been fuelled by the Omicron variant, which is highly infectious yet milder, causing flu-like symptoms such as fever, body pain and sore throat - requiring mostly over-the-counter medications such as paracetamol and multivitamin pills.
As Omicron infections zoom, so does Dolo's market share
Even as the country faces an alarming increase in Covid-19 infections primarily due to the Omicron variant, Dolo 650 has seen high demand as those with fever and body ache scramble to keep the pain away.
No painkillers or paracetamol recommended after Covaxin jab: Bharat Biotech
Stating that it has received feedback that certain immunisation centres are recommending taking three paracetamol 500mg tablets along with Covaxin for children, the company clarified that such a step was not required.
Venus Remedies wins legal battle against French firm for paracetamol patent
The Indian drug firm had initiated the legal battle in order to remove any patent hurdle in manufacturing of intravenous paracetamol solution in the country.
In a race with HCQ, remdesivir and Coronil, Paracetamol has witnessed a sudden rise in demand
Sudden demand for paracetamol has been taken to be a possible clue to people concealing Covid-19 at home. People who have, or think they have, a mild case of Covid are staying at home and taking it. And those who don’t want to be thought to have Covid are taking it too, like travellers who don’t want to be quarantined.
Government frees exports of Paracetamol APIs
The Directorate General of Foreign Trade amended the export policy for Paracetamol APIs to remove the restriction making its export “free with immediate effect. DGFT had restricted the exports of 26 bulk drugs and their formulations on March 3 to ensure there is no shortage of drugs in India but had freed 24 of them in April.
India to send nearly 1,000 tonnes of paracetamol raw material to Europe
The Indian government in March put a hold on exports of several drugs including paracetamol to secure supplies for its people after the coronavirus outbreak disrupted the industry's supply chain globally. COVID-19 is the respiratory disease caused by the novel coronavirus.
Govt lifts curbs on exports of formulations made from Paracetamol
The government on March 3 had put export restrictions on 26 pharma ingredients and medicines, including paracetamol. However on April 6, it removed the export restrictions on 24 APIs and formulations excluding Paracetamol. However, restrictions on exports of Paracetamol active pharmaceutical ingredients (APIs or raw materials) will continue.
Interstate curbs, suspended port ops choke drug supply
Restricted interstate movement and suspended port operations have hindered the supply of key medicines and drugs, including hydroxychloroquine and paracetamol with almost $1 billion of them stuck at the JNPT alone.
Coronavirus outbreak: Your paracetamol supply depends a lot on China
India spooked the world this week by announcing curbs on exports of common drugs including paracetamol.
Don't give paracetamol to infants: It may up asthma risk in adulthood
Paracetamol use is linked to reduced lung function in children after the age of 18.
Paracetamol, injections to cost as much as 35% less
Injections are more commonly used in cases of high fever from dengue and chikungunya. Government data till September 18 shows 78 people died of dengue across the country.
Paracetamol useless in relieving low back pain
The study on paracetamol found that there was never a systematic review of the evidence for the drug's usage to treat low back pain.
Indian Medical Association issues guidelines on the use of painkillers
IMA issued guidelines on safety and efficacy of non-steroidal, anti-inflammatory drugs (NSAIDs) or painkillers in an attempt to clear misconceptions.
India slaps $787 per tn anti-dumping duty on Chinese paracetamol
India has imposed anti-dumping duty of $787 per tonne on import of Paracetamol, a widely used medicine, from China for five years.
First long acting paracetamol pill launched
The Paracetamol molecule has been formulated after extensive research in such a way that it will have 20 per cent less toxicity levels.
Bafna Pharma bags UK nod for Paracetamol, Loperamide
Bafna Pharmaceuticals on Thursday said it has received approval from the UK health regulator to produce popular drug Paracetamol and Loperamide capsules.
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